Clinical Research

ORTHOPEDIC (OSTEOARTHRITIS & INJURIES)

Mesenchymal stem cells (MSCs) are self-renewing, multi-potent, progenitor cells with multi-lineage potential to differentiate into cell types of mesodermal origin. Due to this attribute, MSCs can differentiate into chondrocytes, which are later replaced by bone. This attribute repairs the subchondral bone without any loss of articular cartilage at the surface.

MSCs have shown to therapeutically alter the progression of OA by down-modulating the release and expression of the main OA inflammatory factors and chemokines (signaling proteins secreted by cells) directly involved in the progression of the disease. Additionally, there has been significant improvement in joint function through pain reduction and increase of cartilage in the affected joint.

Read Our Articles

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A Randomized Controlled Trial Of The Treatment Of Rotator Cuff Tears With Bone Marrow Concentrate.

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ACL Tear Treated With BMAC.

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Adult Mesenchymal Stem Cells For The Treatment In Patients With Rotator Cuff Disease.

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Increased Knee Cartilage Using Stem Cells.Pdf

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Knee Cartilage Repair Review 2019

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Treatment Of Shoulder Osteoarthritis And Rotator Cuff Tears With Bone Marrow Concentrate And Whole Bone Marrow Injections.

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A Prospective, Single-Blind, Placebo-Controlled Trial Of Bone Marrow Aspirate Concentrate For Knee Osteoarthritis

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Knee Osteoarthritis A Randomized Controlled Trial With 2 Year Follow Up.

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Mesenchymal Cell Therapy Ortho-Biologics In The Treatment Of Hip Osteoarthritis.

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Mesenchymal Stem Cells Injection In Hip Osteoarthritis.

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Cell Therapy Ortho-Biologics In The Management Of Shoulder Rotator Cuff Disorders.

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The Healing Effect Of Bone Marrow Derived Stem Cells In Knee Osteoarthritis.

DEGENERATIVE DISC DISEASE

Adipose derived Cell Therapy Ortho-Biologics uses Mesenchymal Stem Cells (MSCs) to significantly display long-term proliferation, efficient self-renewal, and multi-potent differentiation. Meaning the MSCs have the ability to end and reverse degeneration of spinal discs. More specifically through increasing disc height by 23.6%, disc water content, and gene expression. One of the main biological functions of MSCs is their ability to reproduce cartilage and bone tissue cells (multi-potent differentiation capability). This is important in degenerative disc disease, since a large number of cells from the outer ring (annulus fibrosus) and the inner gelatinous (nucleus pulposus) of the discs are of a cartilaginous nature.

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Autologous Bone Marrow Concentrate Cells Significantly Reduces Lumbar Discogenic Pain Through 12 Months.

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Stem Cell Treatment For Discogenic Low Back Pain And Disc Degeneration.

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Stem Cells Sources For Intervertebral Disc Regeneration.

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Treatment Of Lumbar Degenerative Disc Disease-Associated Radicular Pain With Autologous Stem Cells.

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Stem Cells In Preclinical Spine Studies

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Cell Therapy For Age Related Intervertebral Disc Pathologies Disc

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