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If you’re dealing with ongoing knee pain and looking for a non-surgical option, genicular artery embolization (GAE) might be something you’ve come across.
It’s a minimally invasive procedure that helps relieve pain, especially for people with knee osteoarthritis.
But like any procedure, it’s normal to wonder about possible side effects.
In this guide, we’ll walk through what you can expect, how long side effects usually last, and how we help you recover smoothly at Orthobiologics Associates.
GET RELIEF WITH THE GAE PROCEDURE
What Is Genicular Artery Embolization (GAE)?
Genicular artery embolization is a targeted procedure that reduces inflammation and pain by blocking small blood vessels in the knee.
These vessels, called genicular arteries, supply blood to the inflamed areas of the knee joint.
By limiting that blood flow, we can reduce the pain signals being sent to the brain—without having to rely on surgery or joint replacement.
It’s typically done for people with chronic knee pain who haven’t found relief from other treatments and want to avoid surgery.
The GAE knee procedure is quick, done through a tiny incision, and most people go home the same day.
Common Side Effects of Genicular Artery Embolization
Most people tolerate GAE well, but it’s helpful to know what side effects may happen during recovery.
The good news is they’re usually mild and temporary.
Some of these Genicular Artery Embolization side effects include:
Mild pain or swelling near the insertion site
You might feel some soreness or notice slight swelling where the catheter was placed, usually in the upper thigh or groin.
This typically fades within a few days and responds well to rest and over-the-counter pain relievers.
Skin discoloration or bruising
Some bruising around the access point or knee is common.
This is a normal reaction and should clear up within a week or two.
Temporary numbness or tingling
Occasionally, people report a tingling or slightly numb feeling in the knee.
This is usually short-lived and goes away as the knee continues to heal.
Rare but Possible Complications of GAE
While GAE is considered low-risk, rare complications can happen.
We take every precaution to keep these risks low.
Non-target embolization
This means the particles used during the procedure travel to areas outside the intended zone.
At Orthobiologics Associates, we use precise image guidance to focus only on the arteries that are contributing to your pain.
Infection or bleeding
As with any minimally invasive procedure, there’s a small chance of infection or bleeding.
We take sterile precautions, and any post-procedure care instructions are designed to prevent this.
Reaction to contrast dye
Some people may react to the dye used during imaging.
If you’ve had dye-related issues before, we’ll talk with you in advance about the safest plan moving forward.
How Long Do Side Effects Typically Last?
Most side effects resolve quickly.
Pain, swelling, or bruising around the catheter site usually improves in just a few days.
Any tingling or numbness in the knee tends to go away within a week or two.
Relief from knee pain can begin as soon as a few days after the procedure, with continued improvements over several weeks.
If something feels off—like new swelling, redness, a fever, or pain that’s getting worse—it’s a good idea to check in with your provider.
Is Genicular Artery Embolization Safe?
Yes, GAE is a safe and effective option for many people dealing with chronic knee pain.
It avoids the risks of major surgery and doesn’t require a lengthy recovery.
Compared to knee replacement, the side effects of genicular artery embolization are typically fewer, milder, and easier to manage.
Many people choose GAE because it gives them the chance to stay active, delay or avoid surgery, and get meaningful relief from pain with little downtime.
How We Help You Avoid Risks at Orthobiologics Associates
At Orthobiologics Associates, we take a personalized, image-guided approach to GAE.
That means better accuracy, fewer complications, and better outcomes.
Here’s how we help you stay safe and recover comfortably:
- We use advanced imaging to precisely target the arteries causing your pain
- Our team has extensive experience performing GAE safely and effectively
- We screen thoroughly before the procedure to reduce any potential risks
- You’ll receive step-by-step recovery instructions and ongoing support after treatment
You’re not just a number—we’re here to help you feel better and get back to doing what you love.
Schedule a consultation with us to learn more today!
What to Expect After Genicular Artery Embolization
After the procedure, most people rest for a short time and then go home the same day.
You may feel tired or notice some mild discomfort in the area where the catheter was inserted.
That’s completely normal.
Here are a few tips for recovery:
- Take it easy for the first 24 to 48 hours
- Avoid heavy lifting or intense activity for about a week
- Drink water and take short walks to help with circulation
Pain relief often starts within a few days.
Many people continue to feel better over the next month or two.
Conclusion: Genicular Artery Embolization Side Effects
We always want you to feel confident during recovery.
If you notice symptoms like fever, increased redness or swelling, or worsening pain, don’t wait—reach out to your care team.
We’re here to support you every step of the way.
FAQs: Genicular Artery Embolization Side Effects
Can GAE help with a failed knee replacement?
GAE is not typically used to treat failed knee replacements, but it may help in specific cases where pain is coming from inflammation rather than mechanical issues. A detailed evaluation is needed to determine if GAE is a good fit.
Can GAE help with osteoarthritis?
Yes, GAE is most commonly used for people with knee osteoarthritis. It works by reducing inflammation in the joint, which can significantly reduce pain and improve mobility.
How long does GAE last?
Studies show results of GAE that can last for 6 to 24 months or longer, depending on the severity of the arthritis and how your body responds. Some people may need repeat treatment down the line.
Is the GAE procedure safe?
GAE is considered a safe, low-risk procedure when performed by trained specialists using image guidance. Most side effects are mild and temporary.
How long does it take for GAE to work?
Many people begin to notice pain relief within the first week or two, with continued improvement over the next one to two months.
What are the benefits of GAE?
GAE offers targeted pain relief without the need for surgery. It’s minimally invasive, has a short recovery time, and can delay or even prevent the need for joint replacement in some patients.
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